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Antifreeze / engine coolant (ethylene glycol-based) — household safety profile

Extreme risk

Engine coolant containing 90-95% ethylene glycol (EG) with corrosion inhibitors, dyes, and anti-foaming agents.

What is this product?

Engine coolant containing 90-95% ethylene glycol (EG) with corrosion inhibitors, dyes, and anti-foaming agents. Ethylene glycol has a sweet taste that attracts children and animals. Ingestion of as little as 100 mL can be fatal to an adult (LD50 ~1.4 mL/kg). EG is metabolized to glycolic acid and oxalic acid, causing metabolic acidosis, renal tubular necrosis, and death. Leading cause of poisoning death from automotive products. Approximately 6,000 US poison exposures annually, with ~90 deaths.

What's in it

Click any compound name for its full safety profile, regulatory consensus, and exposure data.

Primary active ingredients

  • Ethylene glycol (antifreeze) — Sweet-tasting. Fatal dose ~100 mL (adult), ~1.5 mL/kg. Metabolized to glycolic acid and oxalic acid causing metabolic acidosis, CNS depression, and acute renal failure. Treatment: fomepizole or ethanol (competitive ADH inhibition) + hemodialysis.

How to use it more safely

  • Use only in closed cooling systems
  • Clean up all spills immediately and thoroughly
  • Store in locked cabinet away from children and pets
  • Use products with bittering agent (denatonium benzoate)

Red flags — when to walk away

  • Open container of brightly colored fluidSweet-tasting lethal poison accessible to children/pets

Green flags — what to look for

  • 'Bittered' or denatonium benzoate on labelBittering agent reduces (but does not eliminate) accidental ingestion risk

Safer alternatives

  • Propylene glycol-based antifreeze — Much lower toxicity (LD50 ~20 mL/kg vs. ~1.4 mL/kg for EG); still not safe to drink but significantly less hazardous
  • Pre-diluted (50/50) coolant — Half the ethylene glycol concentration of concentrate; reduces but does not eliminate poisoning risk

Frequently asked questions

What's in Antifreeze / engine coolant (ethylene glycol-based)?

This product type can contain: Ethylene glycol, among others. Click any compound name above for the full safety profile.

How can I use Antifreeze / engine coolant (ethylene glycol-based) more safely?

Use only in closed cooling systems; Clean up all spills immediately and thoroughly; Store in locked cabinet away from children and pets

Are there safer alternatives to Antifreeze / engine coolant (ethylene glycol-based)?

Yes — consider: Propylene glycol-based antifreeze; Pre-diluted (50/50) coolant. See the Safer alternatives section above for details.

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Reference data, not professional advice. Aggregates publicly available regulatory and scientific information. Why we built ALETHEIA →