Home Safety / Compounds / Sulfur dioxide (SO₂)

Sulfur dioxide (SO₂) in your home: a safety profile

High risk for your home

Inhalation is the primary route for environmental and occupational exposure. SO₂ is highly water-soluble; most is absorbed in the upper airways, but sufficient concentrations reach the lower respiratory tract to cause bronchospasm and mucous secretion. Occupational IDLH 100 ppm; OSHA PEL 5 ppm. Acute high-dose exposure in industrial accidents (e.g., cooling system failures using SO₂ refrigerant) causes severe pulmonary edema, potentially fatal. Asthmatics respond at far lower concentrations than healthy adults — NAAQS designed to protect this sensitive subpopulation. Historical 'killer smogs' (London 1952: ~4,000 excess deaths) involved extreme SO₂ + fog + PM synergy.

What is sulfur dioxide (so₂)?

The IUPAC name is sulfur dioxide.

Also known as: sulfur dioxide, sulphur dioxide, Sulfurous anhydride, Sulfurous oxide.

IUPAC name
sulfur dioxide
CAS number
7446-09-5
Molecular formula
O2S
Molecular weight
64.07 g/mol
SMILES
O=S=O
PubChem CID
1119

Risk for your household

High risk

Inhalation is the primary route for environmental and occupational exposure. SO₂ is highly water-soluble; most is absorbed in the upper airways, but sufficient concentrations reach the lower respiratory tract to cause bronchospasm and mucous secretion. Occupational IDLH 100 ppm; OSHA PEL 5 ppm. Acute high-dose exposure in industrial accidents (e.g., cooling system failures using SO₂ refrigerant) causes severe pulmonary edema, potentially fatal. Asthmatics respond at far lower concentrations than healthy adults — NAAQS designed to protect this sensitive subpopulation. Historical 'killer smogs' (London 1952: ~4,000 excess deaths) involved extreme SO₂ + fog + PM synergy.

Regulatory consensus

13 regulatory and scientific bodies have classified Sulfur dioxide (SO₂). The classifications differ — that's the data.

AgencyYearClassificationNotes
WHOcriteria air pollutant
US EPAcriteria air pollutant
IARCnot classified as a carcinogen
EPA CTX / IARCGroup 3 - Not classifiable as to its carcinogenicity to humans
EPA CTX / GenetoxGenotoxicity: positive (Ames: None, 3 positive / 1 negative reports)
EPA CTX / GenetoxGenotoxicity: positive (Ames: None, 3 positive / 1 negative reports)
EPA CTX / Skin-EyeSkin Irritation: Skin Corr. 1B (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Skin corrosion/irritation - Category 1 (score: very high)
EPA CTX / Skin-EyeEye Irritation: Category 2A (score: high)
EPA CTX / Skin-EyeEye Irritation: Eye Dam. 1 (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Skin Corr. 1B (score: very high)
EPA CTX / Skin-EyeEye Irritation: Category 8.3A (Category 1) (score: very high)
EPA CTX / Skin-EyeSkin Irritation: Category 8.2B (Category 1B) (score: very high)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where your home encounter sulfur dioxide (so₂)

  • Outdoor AirVehicle exhaust, Industrial emissions, Power plant discharge
  • Indoor AirCombustion byproducts, Office buildings, Parking garages

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Sulfur dioxide (SO₂):

  • Physical/mechanical pest control (IPM)
    Trade-offs: More labor-intensive. May not be sufficient for severe infestations.
    Relative cost: 1.2-2×

Frequently asked questions

Is sulfur dioxide (so₂) safe for your home?

Inhalation is the primary route for environmental and occupational exposure. SO₂ is highly water-soluble; most is absorbed in the upper airways, but sufficient concentrations reach the lower respiratory tract to cause bronchospasm and mucous secretion. Occupational IDLH 100 ppm; OSHA PEL 5 ppm. Acute high-dose exposure in industrial accidents (e.g., cooling system failures using SO₂ refrigerant) causes severe pulmonary edema, potentially fatal. Asthmatics respond at far lower concentrations than healthy adults — NAAQS designed to protect this sensitive subpopulation. Historical 'killer smogs' (London 1952: ~4,000 excess deaths) involved extreme SO₂ + fog + PM synergy.

What products contain sulfur dioxide (so₂)?

Sulfur dioxide (SO₂) appears in: Vehicle exhaust (Outdoor air); Industrial emissions (Outdoor air); Combustion byproducts (Indoor air); Office buildings (Indoor air).

Why do regulators disagree about sulfur dioxide (so₂)?

Sulfur dioxide (SO₂) has been classified by 13 agencies including WHO, US EPA, IARC, EPA CTX / IARC, EPA CTX / Genetox, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Sulfur dioxide (SO₂) in the home app

Look up products containing sulfur dioxide (so₂), compare to alternatives, and explore the full data record.

Open in home View raw API data

Sources (3)

  1. US EPA National Ambient Air Quality Standards for Sulfur Dioxide (2010) — regulatory
  2. WHO Air Quality Guidelines for Sulfur Dioxide (Global Update 2021) (2021) — regulatory
  3. ATSDR Toxicological Profile for Sulfur Dioxide (1998) — report

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →