Home Safety / Compounds / Dimethyl phthalate

Dimethyl phthalate in your home: a safety profile

Low risk for your home

Not medical or professional safety advice, and not a substitute for a qualified clinician — consult one. Full disclaimer →

Indoor-air migration from cellulose-acetate plastics and pharmaceutical-coating formulations; secondary route to dermal application.

What is dimethyl phthalate?

The IUPAC name is dimethyl benzene-1,2-dicarboxylate.

Also known as: dimethyl benzene-1,2-dicarboxylate, DIMETHYLPHTHALATE, Avolin, Mipax.

IUPAC name
dimethyl benzene-1,2-dicarboxylate
CAS number
131-11-3
Molecular formula
C10H10O4
Molecular weight
194.18 g/mol
SMILES
COC(=O)C1=CC=CC=C1C(=O)OC
PubChem CID
8554

Risk for your household

Low risk

Indoor-air migration from cellulose-acetate plastics and pharmaceutical-coating formulations; secondary route to dermal application.

Regulatory consensus

5 regulatory and scientific bodies have classified Dimethyl phthalate. The classifications differ — that's the data.

AgencyYearClassificationNotes
US EPA (IRIS)2010not classifiable as to human carcinogenicity (Group D); oral RfD 10 mg/kg/day; inadequate data to assess carcinogenicity
EPA CTX / IRISD (Not classifiable as to human carcinogenicity)
EPA CTX / EPA OPPGroup D Not Classifiable as to Human Carcinogenicity
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 0 positive / 12 negative reports)
EPA CTX / GenetoxGenotoxicity: negative (Ames: negative, 0 positive / 12 negative reports)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where your home encounter dimethyl phthalate

  • Consumer ProductsPlastic bottles and containers, Food packaging, Plastic toys and household items
  • Drinking WaterLeaching from plastic pipes, Migration from bottled water containers
  • Indoor EnvironmentsOff-gassing from plastic furniture, Degradation of plastic products

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Dimethyl phthalate:

  • Fragrance-free formulations
    Trade-offs: Consumer preference for scented products
    Relative cost: Lower (ingredient elimination)
  • Essential oil-based fragrances (with disclosure)
    Trade-offs: Natural does not mean safe — many essential oils are skin sensitizers
    Relative cost: 2-5× conventional

Frequently asked questions

Is dimethyl phthalate safe for your home?

Indoor-air migration from cellulose-acetate plastics and pharmaceutical-coating formulations; secondary route to dermal application.

What products contain dimethyl phthalate?

Dimethyl phthalate appears in: Plastic bottles and containers (Consumer products); Food packaging (Consumer products); Leaching from plastic pipes (Drinking water); Migration from bottled water containers (Drinking water); Off-gassing from plastic furniture (Indoor environments).

Why do regulators disagree about dimethyl phthalate?

Dimethyl phthalate has been classified by 5 agencies including US EPA (IRIS), EPA CTX / IRIS, EPA CTX / EPA OPP, EPA CTX / Genetox, EPA CTX / Genetox, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.

See Dimethyl phthalate in the home app

Look up products containing dimethyl phthalate, compare to alternatives, and explore the full data record.

Open in home View raw API data

Sources (2)

  1. US EPA IRIS Dimethyl Phthalate: Group D Not Classifiable Carcinogenicity; Oral RfD 10 mg/kg/day; Kidney Liver Effects; Low log Kow ~1.6; Rapid Hydrolysis to Monomethyl Phthalate (2010) — regulatory
  2. WHO Insect Repellents Safety: DMP Historical Military Use; Skin Application Without Significant Adverse Effects; Lower Concern Phthalate vs DEHP DBP; Not in EFSA Cumulative Phthalate Group (2009) — regulatory

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for medical, legal, or regulatory advice. Why we built ALETHEIA →