Bisphenol AF (BPAF) in your home: a safety profile
Low risk for your homeNot medical or professional safety advice, and not a substitute for a qualified clinician — consult one. Full disclaimer →
Low vapor pressure; inhalation is not a significant route outside fluoroelastomer and high-performance-polymer manufacturing.
What is bisphenol af (bpaf)?
The IUPAC name is 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol.
Also known as: 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol, Bisphenol AF, 2,2-Bis(4-hydroxyphenyl)hexafluoropropane, Hexafluorobisphenol a.
- IUPAC name
- 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol
- CAS number
- 1478-61-1
- Molecular formula
- C15H10F6O2
- Molecular weight
- 336.23 g/mol
- SMILES
- C1=CC(=CC=C1C(C2=CC=C(C=C2)O)(C(F)(F)F)C(F)(F)F)O
- PubChem CID
- 73864
Risk for your household
Low riskLow vapor pressure; inhalation is not a significant route outside fluoroelastomer and high-performance-polymer manufacturing.
Regulatory consensus
6 regulatory and scientific bodies have classified Bisphenol AF (BPAF). The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| EPA CTX / Genetox | — | Genotoxicity: negative (Ames: negative, 0 positive / 4 negative reports) | |
| EPA CTX / Genetox | — | Genotoxicity: negative (Ames: negative, 0 positive / 4 negative reports) | |
| EPA CTX / Skin-Eye | — | Eye Irritation: Category 6.4A (Category 2A) (score: high) | |
| EPA CTX / Skin-Eye | — | skin irritation: in vivo: Studies Indicate No Significant Irritation (score: low) | |
| EPA CTX / Skin-Eye | — | eye irritation: in vivo: Corrosive or Irritation Persists for > 21 days (score: very high) | |
| EPA CTX / Skin-Eye | — | skin sensitisation: in vivo (non-LLNA): Not likely to be sensitizing (score: low) |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where your home encounter bisphenol af (bpaf)
- Consumer Products — Plastic bottles and containers, Food packaging, Plastic toys and household items
- Drinking Water — Leaching from plastic pipes, Migration from bottled water containers
- Indoor Environments — Off-gassing from plastic furniture, Degradation of plastic products
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Bisphenol AF (BPAF):
-
Calcium carbonate or kaolin fillers
Trade-offs: Different performance characteristics than specialty fillers.Relative cost: 1.2-2×
Frequently asked questions
Is bisphenol af (bpaf) safe for your home?
Low vapor pressure; inhalation is not a significant route outside fluoroelastomer and high-performance-polymer manufacturing.
What products contain bisphenol af (bpaf)?
Bisphenol AF (BPAF) appears in: Plastic bottles and containers (Consumer products); Food packaging (Consumer products); Leaching from plastic pipes (Drinking water); Migration from bottled water containers (Drinking water); Off-gassing from plastic furniture (Indoor environments).
Why do regulators disagree about bisphenol af (bpaf)?
Bisphenol AF (BPAF) has been classified by 6 agencies including EPA CTX / Genetox, EPA CTX / Genetox, EPA CTX / Skin-Eye, EPA CTX / Skin-Eye, EPA CTX / Skin-Eye, with differing conclusions. Regulators apply different standards of evidence (animal data weighting, exposure-pattern assumptions, epidemiological power thresholds), which is why two scientific bodies can review the same data and reach different conclusions. See the regulatory consensus table on this page for the full picture.
See Bisphenol AF (BPAF) in the home app
Look up products containing bisphenol af (bpaf), compare to alternatives, and explore the full data record.
Open in home View raw API dataSources (2)
- US EPA: Bisphenol AF — CompTox Chemical Dashboard Assessment and Endocrine Disruption Screening (2020) — regulatory
- WHO/UNEP: State of the Science of Endocrine Disrupting Chemicals — Emerging Bisphenol Analogs and Industrial EDC Burden (2012) — regulatory
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for medical, legal, or regulatory advice. Why we built ALETHEIA →